Modern nanotechnology enables the bottom-up construction of molecular machines and nanorobots using two different nanoworld Lego-bricks, DNA or peptides. Combining the power of these two nanoworld codes may kindle the onset of a next-generation nanotechnology for various chemical and biological applications.
My research group is dedicated to taming DNA and peptide to develop more powerful molecule tools to unveil the molecular mechanisms of long-lasting scientific questions in fundamental research, and to develop innovative molecular machines for diagnostic and therapeutic applications.
The group is currently working on the following four research directions: 1) to delineate the elusive protein-protein interactions implicated in the difficult-to-cure diseases such as Alzheimer’s disease, Parkison’s disease and type-2 diabetes; 2) to identify new small-molecule hits for those difficult-to-cure diseases; 3) To develop novel molecular tools to precisely silence the diseasing-causing genes for therapeutic applications; 4) to use chemically modified DNA nanoclusters for bioimaging applications.
Research cooperation:
